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[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Knezevic M., Gojkovic S., Krezic I., Zizek H., Malekinusic D., Vrdoljak B., Knezevic T., Vranes H., Drmic D., Staroveski M., et al

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As previously mentioned, ghrelin is the only known mediator that has a stimulatory effect on orexigenic neurons, whereas many other peripheral signals negatively influence appetite